The screen does not respond to touches — what happened?
Most likely lock mode is on: touches on the map and buttons are deliberately ignored so you do not accidentally move the chosen point. To exit, long-press the screen.
The mode is handy when the phone is in a pocket or a holder with spoofing active: any accidental touch in that state could move the point or stop spoofing.
When the mode is turned on, the app shows a hint on how to exit it. Spoofing keeps working normally in this mode — only input is blocked.